Ep. 110: The True Cause of Insulin Resistance and Diabetes from the Bioenergetic View

In this episode we discuss:

• Why insulin resistance and diabetes are not caused by excess carbohydrate consumption and are not actually an insulin signaling problem 
• The problems with the idea of metabolic flexibility, earning your carbs, and the carb-insulin model of obesity 
• Why carbs are beneficial even for people who have insulin resistance or diabetes 
• The role of fat burning and stress in driving insulin resistance 
• Specific diet, movement, and supplement recommendations to reverse insulin resistance and diabetes 

 

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Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-110-the-true-cause-of-insulin-resistance-and-diabetes-from-the-bioenergetic-view/

 

Timestamps:

0:00 – intro

1:14 – metabolic flexibility, earning your carbs, the carb-insulin model of obesity, and dispelling other common insulin resistance myths

7:48 – low-carb, keto, and carnivore diets may improve symptoms but are not the solution for insulin resistance

13:13 – what the mainstream views of insulin resistance gets wrong when it comes to what causes insulin resistance

15:50 – why you might not want to use a continuous glucose monitor and the unnecessary fear of blood glucose spikes

17:48 – whether insulin is harmful and whether we want to keep insulin levels as low as possible

22:15 – whether we can restore optimal insulin sensitivity without low-carb diets 

25:16 –the bioenergetic view of insulin resistance 

27:12 – insulin resistance as an adaptive evolutionary process that is crucial for survival

31:22 – the difference between physiological and pathological insulin resistance

34:40 – how inhibited glucose oxidation causes insulin resistance

40:46 – how fatty acid oxidation causes increased production of ROS, slows cellular respiration, and blocks glucose oxidation (The Randle Cycle)

51:06 – the harms of ROS production from fatty acid oxidation and other forms of stress

53:04 – insulin resistance as an energy deficient state

54:19 – insulin resistance is not an insulin signaling problem, it’s an energy production problem 

58:30 – the role of stress hormones (like cortisol) in insulin resistance 

1:02:09 – how insulin and carbohydrates decrease stress 

1:05:59 – how to fix insulin resistance and restore insulin sensitivity by fixing our capacity to produce energy  

1:10:38 – specific diet, movement, and supplementation recommendations for insulin resistance and diabetes 

1:17:55 – why you don’t need to tailor your carb intake to your carb tolerance