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Discover how you can live without constant hunger and fatigue, brain fog, poor sleep, and other low-energy symptoms. The Energy Balance Podcast will teach you how to maximize your cellular energy so you can take back your health and finally experience clear-headed focus, restful sleep, and all-day energy you didn’t think was possible.
Episodes

Friday Jul 14, 2023
Friday Jul 14, 2023
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Why hypothyroidism is not the root cause of your issues
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Why TSH on its own is not a good marker of thyroid status
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The importance of thyroid hormones for sex hormone production, gut health, and immune function
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T3’s effects on autophagy, mitochondrial biogenesis, and uncoupling
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Whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign
Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-95-hypothyroidism-in-context-thyroid-hormone-basics-hypothyroidism-part-1/
Timestamps:
0:00 – intro
1:19 – an introduction to hypothyroidism and common symptoms of hypothyroidism
9:02 – the broader biological context of hypothyroidism and hypothyroidism as a low metabolic state
12:45 – why hypothyroidism is not the root cause
16:23 – the basics of the different thyroid hormones and their regulation
19:54 – the hypothalamic-pituitary-thyroid axis and the nuances within the negative feedback loops
24:45 – the basics of thyroid hormone production
29:37 – the basics of thyroid hormone conversion
35:17 – the larger context of thyroid hormone production and conversion
38:58 – the basics of thyroid hormone transport
41:44 – the basics of thyroid hormone uptake
46:23 – the nutrients involved in thyroid hormone production and conversion
50:26 – the cellular effects of T3 (metabolic stimulation, uncoupling, autophagy, mitochondrial biogenesis, steroidogenesis from cholesterol)
57:29 – the effects of T3 on gut health, immune function, and aging
1:03:08 – whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign
1:08:41 – the relationship between vitamin A and thyroid hormones

Thursday Jul 06, 2023
Thursday Jul 06, 2023
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Why uncoupling is harmful in certain contexts and how PUFA cause constant, low-level uncoupling
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The involvement of uncoupling, mitochondrial biogenesis, autophagy, heat shock proteins, and hypoxia-inducible factors in the stress response
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How stress prevents our mitochondria from effectively producing energy
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How chronic stress causes insulin resistance, high blood pressure, weight gain, depression, and cardiovascular disease
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How sugar and fat cravings result from stress and why listening to them is beneficial
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How adaptations to stress get passed on through generations
Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-94-how-stress-crashes-your-metabolism-why-hormesis-is-not-the-answer-stress-mitochondria-part-2/
Timestamps:
0:00 – intro
2:59 – the details of how mitochondrial respiration can become disrupted, especially from glucocorticoids
6:05 – the short-term effects of catecholamines
8:34 – why uncoupling is harmful in certain contexts and how PUFA cause constant, low-level uncoupling
14:40 – the protective effects of uncoupling as a part of the stress response
20:08 – the role of cytokines (TNF-alpha, IL-1, IL-6, heat-shock proteins, NF-kB, HIF) in the stress response
37:33 – the effect of acute stress on energy production in mitochondria
45:18– the effect of chronic stress on energy production in mitochondria
48:15 – how stress drives degeneration and the evidence for increased activity of hormetic pathways (including effects like mitochondrial biogenesis and autophagy) in degenerative states
1:05:24 – the relationship between mental health, mood, and metabolic function
1:10:21 – how adaptations to stress get passed on through mitochondrial DNA
1:18:32 – how to best improve mitochondrial function and our health

Tuesday Jun 27, 2023
Tuesday Jun 27, 2023
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Why stress is not your friend
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The effects of cortisol on your mitochondria
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Hans Selye’s general adaptation syndrome
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How cortisol causes mitochondrial dysfunction, heart disease, insulin resistance, autoimmunity, allergies & hypersensitivity, mineral imbalances, and cancer metabolism
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Why acute stress does not lead to improved health via hormesis
Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-93-how-cortisol-affects-your-mitochondria-acute-vs-chronic-stress-stress-mitochondria-part-1-ep-93/
Timestamps:
3:00 – an introduction to the paper: mitochondria as key components of the stress response
4:03 – Hans Selye’s general adaptation syndrome and the process of stress in relation to energy balance
23:30 – the 3 main effects of the stress hormones in the acute stress response and the cost to this response
31:48 – long-term glucocorticoid exposure causes insulin resistance and the protective effects of high blood sugar in certain contexts
34:04 – how long-term stress causes degeneration
34:55 – functions of the mitochondria
38:54 – mitochondria upregulate energy production in response to stress
41:06 – the short-term vs. long-term effects of the glucocorticoids (cortisol)
44:03 – how stress causes hormetic adaptations and how the hormetic pathways cause degeneration over time
50:30 – how mitochondria respond to excess stress and how this relates to fat gain
59:04 – how chronic stress and exposure to cortisol causes impaired energy production, degeneration, immunosuppression & autoimmunity, mineral imbalance, swelling, allergies & hypersensitivity, and cancer metabolism

Monday Dec 19, 2022
Ep. 92: Celebrating Ray Peat
Monday Dec 19, 2022
Monday Dec 19, 2022
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-92-celebrating-ray-peat/
Ray Peat's Website: http://raypeat.com/
Ray Peat Interviews, Articles, Related Websites, and Other Resources: https://www.selftestable.com/ray-peat-stuff/sites

Tuesday Nov 22, 2022
Tuesday Nov 22, 2022
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Whether cod liver oil is an ideal source of vitamin A/retinol
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Whether we should be concerned about the omega-3 content of cod liver oil (CLO)
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The idea that we want our fat cells to be insulin resistant to lose fat
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Whether keeping insulin low is the key to fat loss
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What hormones regulate fat loss
Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-91-cod-liver-oil-dangers-the-croissant-diet-and-insulin-resistant-fat-cells-q-a/
Timestamps:
2:54 – what we think about cod liver oil as a vitamin A source
9:50 – why someone may benefit from cod liver oil, and why it likely isn’t a result of the retinol
10:56 – the immunosuppressive effects of omega-3s
14:25 – the major problems with omega-3s, including cod liver oil specifically
25:33 – clarifying our thoughts on the Croissant Diet
28:26 – burning saturated fat versus burning PUFA and whether PUFA create more ROS than saturated fats
31:41 – what we think of the idea that consuming saturated fats will allow for fat loss by causing insulin resistance in the adipocytes (fat cells)
42:50 – why increasing fat burning doesn’t inherently lead to increased fat loss
47:11 – whether increasing satiety is the key to fat loss

Monday Nov 07, 2022
Monday Nov 07, 2022
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Whether fish oil is beneficial due to its anti-inflammatory and cholesterol-lowering effects
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Our thoughts on the benefits from a paleo-ketogenic diet
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What to do if you’re dealing with dental issues from sugar consumption
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Our experiences eating 5,000 to 6,000 calories per day
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The best time to eat the carrot salad
Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-90-eating-5000-calories-per-day-fish-oil-water-weight-vs-body-fat-paleo-ketogenic-diet-q-a/
Timestamps:
2:44 – why fish oil shows anti-inflammatory and cholesterol-lowering effects, and why this doesn’t mean they’re beneficial
11:25 – eating carrots with a meal versus away from a meal
17:27 – our thoughts on the benefits from a paleo-ketogenic diet
28:45 – which coral calcium supplement we recommend
32:33 – dental issues from sugar consumption
39:45 – what we think of orange juice with added calcium
41:36 – how to determine whether weight gain is due to water weight or body fat
51:57 – our experiences eating 5,000-6,000 calories per day
1:03:23 – whether it’s helpful to use calorie calculators and context to consider when it comes to calorie calculators
1:11:20 – how our current diets vary in contrast to when we were eating 5,000-6,000 calories per day

Wednesday Oct 12, 2022
Wednesday Oct 12, 2022
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Whether PUFA causes more oxidative stress than saturated fats
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How PUFA intake affects testosterone
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Whether fruit juice should be avoided for blood sugar regulation
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The effects of fruit juice on inflammatory markers and endotoxin
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Whether fruit juice has the same effects as soda
Check out the Energy Balance Solution group coaching program: https://jayfeldmanwellness.com/solution
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-89-the-anti-inflammatory-effects-of-fruit-juice-and-the-hormonal-effects-of-pufa-vs-sfa/
Timestamps:
4:10 – the effects of different dietary fat compositions on phospholipid and neutral lipid compositions in the testicles
18:31 – the effects of different dietary fat composition on oxidative damage and antioxidant status in the testicles
29:44 – the effects of different dietary fat composition on hormone production and metabolism in the testicles
38:26 – introducing the next study discussing the effects of orange juice on a high-fat, high-carbohydrate meal in terms of inflammation and endotoxin
44:14 – the effects of orange juice on blood glucose and insulin sensitivity
47:55 – the effects of orange juice on ROS production, TLR2 and TLR4 expression, and plasma endotoxin
51:35 – factors that could account for the benefits of orange juice

Monday Oct 03, 2022
Ep. 88: Whether Soy Is Estrogenic And Causes Infertility
Monday Oct 03, 2022
Monday Oct 03, 2022
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The hormonal effects of compounds in soy
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How the effects of BPA compare to soy
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Whether soy is estrogenic and causes infertility
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Whether the amount of soy typically consumed is sufficient to create these effects
Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-88-whether-soy-is-estrogenic-and-causes-infertility/
Timestamps:
3:06 – overview of the study we’ll be discussing
5:57 – compounds in soy have potentially estrogenic thymic, immune, and hormonal effects
10:20 – compounds in soy oppose testosterone and reduce its production
13:33 – whether animal research translates to humans
16:40 – BPA has anti-fertility effects in males that are parallel to supplemental estrogen
27:39 – corn oil causes weight gain despite the same number of calories consumed
32:11 – the reproductive effects of soy, BPA, and estradiol
44:50 – the amount of soy required to cause these reproductive effects

Wednesday Aug 17, 2022
Wednesday Aug 17, 2022
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Whether low-carb diets increase cortisol over time
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How the bioenergetic view incorporates evolutionary biology, and how this differs from the ancestral health model
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Whether tolerance to stress is improved on low-carb diets
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Why being overweight or obese is not a sign of excess energy
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What we think of Paul Saladino’s interpretation of the “Ray Peat Diet”
Check out the Energy Balance Solution group coaching program: https://jayfeldmanwellness.com/solution
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-87-robb-wolf-on-ray-peat-and-the-bioenergetic-view-energy-obesity-evolution-and-paul-saladino/
Timestamps:
4:22 – how low-carb diets increase stress hormones and increase susceptibility to stress
22:32 – why being overweight or obese is not a sign of excess energy
34:20 – whether the bioenergetic view ignores evolutionary biology
49:30 – what we think of Paul Saladino’s interpretation of the “Ray Peat Diet”

Monday Aug 08, 2022
Monday Aug 08, 2022
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Whether it’s stressful to be in a fat-burning, keto-adapted state
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How blood sugar is regulated when we’re not eating carbohydrates, and how this impacts stress hormones and thyroid hormones
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Whether having stable blood sugar levels on a low-carb diet is a good thing
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The problems with elevated levels of glucagon, which occurs when someone is on a low-carb diet
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Why glucagon is a stress hormone and its impact on thyroid hormones
Sign up for the Free Energy Balance Mini-Course here: https://jayfeldmanwellness.com/energy
Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-86-robb-wolf-on-ray-peat-and-the-bioenergetic-view-stress-blood-sugar/
Timestamps:
4:30 – why we wanted to discuss Robb Wolf’s perspective of the bioenergetic view
8:25 – Robb’s main points against the bioenergetic view
9:52 – whether fat-burning and being keto-adapted is stressful and how blood sugar is regulated in these states
31:29 – the problems with elevated levels of glucagon, which occurs when someone is on a low-carb diet